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For comparative pharmacology studies requiring simultaneous MT-1 and MT-II treatment groups, prepare each peptide separately in matched vehicles and handle identically to ensure comparability

It activates fibroblasts and increases nitric oxide production to stimulate vascular and connective tissue regeneration [9, 10]

The Registered Human Study ClinicalTrials.gov lists a Phase I safety and pharmacokinetics study under identifier NCT02637284

Table 1 provides a general clinical comparison of these medication classes for the treatment of T2DM