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Tofacitinib also significantly inhibits IL-22-induced CXCL1 and CXCL5 expression in human colonic tissues, suggesting that targeting the IL-22/CXC chemokine axis through JAK/STAT inhibition may be a viable therapeutic strategy

Eur J Cell Biol (2017) 96(3):24053

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Brandes, N., Goldman, G., Wang, C