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Several medications have the potential to restore -cell sensitivity to incretin hormones (Table 1)

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Leslie SW, Soon-Sutton TL, Khan MA Male infertility

Incapsula incident ID: 386000160005837994-24344132357063698

Pattern 2: The Non-Responder (approximately 15% of switchers) Weight loss plateaus or slows despite escalating to Zepbound 12.5 to 15 mg May report initial response at 5 to 7.5 mg that fades by week 16 to 20 Often have underlying metabolic factors (severe insulin resistance, hypothyroidism, medications causing weight gain) For this group, the switch to tirzepatide does not solve the core problem

You can take oral rehydration solution (ORS) to replenish electrolytes and reverse electrolyte imbalance