doi: 10.1016/1043-6618(95)86539-X
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In preclinical models, the peptide has been linked to angiogenesis, which is the formation of new blood vessels, and to fibroblast activity that drives collagen synthesis in healing tissue
Decreased levels of TNF- and IL-6 indicate that NNMT inhibition not only modulates metabolism but also improves the inflammatory microenvironment, a key component in metabolic disease development and insulin resistance
Research involving BPC-157 has extended beyond gastrointestinal physiology into studies of connective and musculoskeletal structures, vascular biology, and cellular adaptation