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Blinding was not performed during animal experiments and data collection, but outcome assessments (e.g., IHC scoring) were conducted by blinded investigators

Second, intrinsic factor, a protein made by stomach cells, binds the freed B12 so it can be absorbed in the small intestine

Young males displayed also higher NADP + /NADPH ratio in frozen blood compared to age-matched females, while NADH and GSSG were higher and GSH/GSSG ratio lower in 31-40 years old males compared to females (Supplementary figure 2i-s)

10.1093/aob/mcl006 Ann

Thus, the UPS is a vital first-line component of PQC, and HSC70 is well known to recruit it when it joins its co-chaperone, CHIP (Shimura et al., 2004

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