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[16] [121] Investigations into the intestinal absorption of B 12 confirm that the upper limit of absorption per single oral dose is about 1.5 g, with 50% efficiency

Age-related changes include reduced gastric acid production (hypochlorhydria or achlorhydria), which impairs the release of B12 from food proteins

In addition, as we age, our ability to absorb B12 from food declines, which puts the elderly at higher risk of deficiency

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