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Animals were monitored for welfare daily, and euthanasia was by cardiac puncture after isoflurane anesthesia

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Targeted modulation and site-specific administration of therapeutic drugs are made possible by the spatiotemporally programmable application of ultrasound, either with or without ultrasound contrast agents [278]

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The modifications that make flmodafinil and fladrafinil more potent than the parent compound also introduce unknown variables regarding their effects on the cardiovascular system, neurological function, and potential for dependence

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