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In fact, neurodegeneration in PD is associated with chronic neuroinflammation controlled essentially by activated microglia (5), as well as molecules released by damaged dopaminergic neurons such as neuromelanin, - synuclein, and active form of matrix metalloproteinase 3 (MMP-3) ( Migraine Pathogenesis: Role of Oxidative Stress, Neuroinflammation, and Mitochondrial Dysfunction Migraine is defined as a neurovascular disorder involving cortical spreading depression (CSD), neurogenic inflammation, and dysfunction in cranial vascular contractility ( Oxidative Stress Oxidative stress role in migraine pathogenesis is emphasized by multiple studies
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McKay, L
