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Semaglutide produced less weight loss than tirzepatide head-to-head, about 14% versus 20%. Its body-composition substudy measured a roughly 62:38 fat-to-lean loss split by mass, compared with about 75:25 for tirzepatide in a separate trial. The scan overstates muscle loss because lean mass includes water and organ tissue

Jun 29 2021;10(13)doi:10.3390/jcm10132896

Schedule I lists drugs or other substance that have a high potential for abuse have no accepted medical use in the United States, and do not have accepted safety guidelines for use

Maintenance dose helps keep your extra weight off and maintains blood sugar levels

Sometimes, a hidden vitamin deficiency is behind these issues

They certainly expected this criteria to be immutable though