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The mucus layer The mucus is a substance composed of water for over 98% and of glycoproteins, such as mucine 2 (MUC2), MUC6, and MUC5A in the stomach and MUC2 in the small and large intestine, secreted by goblet cells

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Thus, going forward, it will be important to focus on dynamic changes observed in those proteins associated with mucosal barrier properties, rather than simply documenting terminal modifications as they are expressed in chronically inflamed mucosa

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