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Recombinant protein yields are further constrained by weak promoters, transcriptional silencing, and proteolytic degradation, while inconsistent glycosylation and post-translational variability can compromise protein stability and bioactivity

While these agents remain largely preclinical, their mechanistic alignment with thyroid-driven fibrosis strengthens their potential utility in hypothyroidism-associated MAFLD

The keywords we used were related to all aspects of preclinical and clinical efficacy and safety data, like lipoic acid or thioctic acid, and pharmacokinetics, pharmacodynamics, safety, toxicity, efficacy, and clinical trials

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Fathizadeh H, Milajerdi A, Reiner , Kolahdooz F, Asemi Z

More than simply measuring your body mass index (BMI), we review personal or family history for thyroid cancer, diabetes, obstructive sleep apnea, or kidney problems