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Sci Rep 7:45963 Von Fricken M, Weppelmann T, Eaton W, Masse R, Madsen VE, De Rochars B et al (2014) Performance of the carestart glucose-6-phosphate dehydrogenase (G6PD) rapid diagnostic test in Gressier, Haiti

G1793A: This polymorphism is rare (~4% prevalence in American women with GG genotype)

A main action is reducing the disulfide bonds in cysteine units in proteins thus reducing the protein while GSH itself is oxidized to GSSH

Downstream Signaling Pathways Following target engagement, AOD 9604 influences intracellular signaling cascades associated with lipid metabolism

However, drugs in this class can increase the risk of heart failure in some people, and may also cause fluid retention in the legs and feet