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Likewise, the average change in FPG through the trial was 37.89 mg/dl (95% CI 52.88 to 22.89 mg/dl) and 35.57 mg/dl (95% CI 48.07 to 23.06 mg/dl) for free up-titration and FRC, respectively, causing insignificant difference (WMD 2.29 mg/dl, 95% CI 45.07 to 40.49 mg/dl

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In dense cultures, disrupting lactate production revealed its key role in reshaping DC functions, leading to increased production of interleukin-12 (IL-12) and decreased interleukin-10 (IL-10)

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These cells release GLP-1 in response to nutrient detection, particularly glucose and lipids, triggering postprandial insulin secretion and satiety signals