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Lipoedema is not a progressive disease, as it does not progress on its own, but is made substantially worse with any weight gain and natural ageing

In contrast, the comparison of the lipid profiles between the HFD group and the HFD + EPA group showed significant increases in EPA, Docosahexaenoic acid (22:6n-3) (DHA), and docosapentaenoate (DPA) (22:5n-3), and significant decreases in stearate and arachidonate (20:4n-6) in the latter group (Table 3)

These results established that tirzepatide monotherapy could achieve glycemic control and weight reduction that exceeded the performance of most combination therapies

2 Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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