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In this review, we comprehensively summarize the mechanisms underlying ferroptosis, discuss novel ferroptosis targets, and evaluate the potential of new ferroptosis-related treatments for ccRCC
Several oncogene-induced cancer cells enhance the antioxidant activity by activating nuclear factor erythroid 2-related factor 2 (NRF2) and maintaining the effect [12, 13, 14, 15, 16]
doi:10.1093/toxsci/kfp126 107
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Regulatory pathway: no IND application filed, no clinical trials registered
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