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159161 In addition, mitochondrial damage may be a contributing factor to the progression of diabetes to AD, as exposure to A Increases the vulnerability of brain mitochondria in diabetic rats

Both GLP-1RAs and SGLT2-Is lower BP, reduce albuminuria, induce weight loss and improve glycaemic control, which all may contribute to their cardiorenal benefits [9, 10]

To reduce discomfort, stick with dietary habits that work for you, such as eating smaller meals, avoiding high-fat foods, staying hydrated, and eating slowly

Additional targets introduce additional interactions, and a stronger average trial result can come with more adverse events, uncertain long-term effects, or a different response across patient groups