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Warning signs of bedsores or pressure ulcers are: Unusual changes in skin color or texture Swelling Pus-like draining An area of skin that feels cooler or warmer to the touch than other areas Tender areas Bedsores fall into one of several stages based on their depth, severity, and other characteristics

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It occurs when mast cells a type of immune cell involved in allergic and inflammatory responses release chemical mediators inappropriately or excessively

Future research should continue to explore the mechanisms underlying the actions of melatonin and its potential applications in clinical settings

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