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Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine

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Even small amounts mixed into the solution destroy peptide function irreversibly

For instance, GSH can be depleted, through inhibition of its synthesis using an inhibitor of GCL (buthionine sulfoximine, BSO) (57) under conditions that maintain the intracellular cysteine pool intact,