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Mutation of R16 to lysine (K) significantly reduced ASYM, whereas single or double mutations of R26 and R68 to K markedly decreased SYM levels

Some research suggests that rapid weight reduction can temporarily influence sleep patterns as the body adjusts to new metabolic demands

Mild side effects such as temporary soreness may occur but are rare

In contrast, food noise describes persistent, intrusive thoughts about food that occur regardless of energy needs