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doi: 10.3389/fonc.2023.1171794 Received 22 February 2023 Accepted 10 April 2023 Published 10 May 2023 Volume 13 - 2023 Edited by Pina Ziranu, University of Cagliari, Italy Reviewed by Stefano Mariani, University of Cagliari, Italy Updates Copyright 2023 Ebeling, Kowalczyk, Perez-Vazquez and Mattiola