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Clinical trials show that combining GLP-1 receptor agonists with metformin produces greater weight loss and blood sugar control than either drug alone
In SURMOUNT-1 , a 72-week Phase 3 double-blind trial in 2,539 adults with obesity (or overweight with a complication) but without diabetes, once-weekly tirzepatide produced mean weight changes of 15.0% (5 mg), 19.5% (10 mg), and 20.9% (15 mg) versus 3.1% with placebo, with 5057% of participants on the higher doses losing at least 20% of body weight
For a 5 mg vial reconstituted with 0.5 mL (also 10 mg/mL), at 2.5 mg per week you get two weeks
If you're considering potential combination therapies like cagrilintide and tirzepatide, or have any other health concerns, take advantage of our free AI doctor visits on our website