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Both produced a noticeable skin-lightening effect, lightening dark spots on the face and skin on the upper forearm

POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases (1, 13)

BY1 promots ferroptosis by enhancing the interaction between NCOA4 and FTH1, leading to increased intracellular ferrous ion levels and subsequent inhibition of vascular restenosis [132]

-220mg of British Vitamin C - 220% of the recommended daily intake

Despite these promising signals, both studies were limited by small sample sizes and short durations, providing only preliminary evidence

Beyond direct transplantation, increasing attention has shifted toward MSC-derived exosomes (MSC-Exos) as acellular, nanoscale delivery vehicles capable of regulating ferroptosis and joint degeneration through paracrine mechanisms (186)