Moreover, the increase in reactive oxygen species (ROS) and reactive nitrogen species (RNS) in endothelial cells due to systemic inflammation might alter claudins and occludins, which are critical structural components of the BBB
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As lipid guidelines broaden the net for statin therapy, automating composite scoring like CTI in EHR workflows provides health systems and primary care networks an immediate objective signal to trigger non-invasive vascular testing (ABI, duplex ultrasound) earlier
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J Allergy 43 , 4554, doi:10.1016/0021-8707(69)90019-7 (1969)