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Third, the numbers of primordial follicles (PMFs) and developing follicles at each stage were significantly lower in the M group than in the control group

The above evidence suggests a dose-dependent neurotoxicity of ketamine, which may be achieved through the upregulation of p-mTOR and its downstream regulators (p-4E-BP-1 and p-p70S6K)

We acknowledge the support of rsula Wyneken (Facultad de Medicina, Universidad de los Andes), Nicols Muoz (CiiB, Universidad de los Andes), and Jean Carol Arce (Doctorado en Biomedicina, Facultad de Medicina, Universidad de los Andes)

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