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The disease is identified by loss of neurons involved in the production of dopamine and located in the substantia nigra pars compacta

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This proved that CaOx activated ferroptosis in HK-2 cells in a concentration-dependent manner

Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway