DISCLAIMER: This guide is for educational purposes only and is not medical advice
Browse discussions, ask questions, and share experiences across hundreds of health topics
However, prolonged use of GH secretagogues can lead to mild desensitization of the GHS-R1a receptor and natural GH axis , which is why taking time off after a cycle is recommended
Those doses are also timed to match the subjects sleep patterns the largest GH pulse gets sent out during sleep, so the last dose of the day comes right before it
But because it is not FDA-approved, any theoretical advantage can be outweighed by practical concerns about product quality and oversight
Adeghate, E., et al.: Neuroendocrinol