thorne l-carnitine - Acetyl-L-Carnitine - 500 mg - Supports Brain Function, Mood & Healthy Nerve Sensations in the Hands & Feet* - Third-Party Certified - Gluten, Dairy & Soy-Free Thorne Acetyl-L-Carnitine

Its like having an extra gym buddy that's always pushing me!" - Sarah

Ethics declarations Competing interests The authors declare no conflict of interest

Indications and Usage: L-Carnitine Injection is indicated for the treatment of carnitine deficiency syndromes, including primary systemic carnitine deficiency, secondary carnitine deficiency, and certain metabolic disorders such as mitochondrial disorders and fatty acid oxidation disorders

Methods Eligibility criteria The PICOS strategy was defined as follows: P (participants) human subjects, I (interventions) oral LC treatment, C (comparisons) between supplementation and placebo, supplementation and control, or pre- and post- supplementation, O (outcomes) muscle variables, and S (study design) randomized controlled trials, non-randomized controlled trials, non-randomized non-controlled trials

The carnitine transporter OCTN2 (novel organic cation transporter 2, SLC22A5) mediates carnitine uptake across the plasma membrane and as such facilitates fatty acid metabolism in most tissues