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Available data comes primarily from animal studies, where the peptide has generally shown a very favorable toxicity profile

Segn las guas de la American Diabetes Association (ADA), los agonistas del receptor GLP-1 con beneficio cardiovascular demostrado se recomiendan para pacientes con diabetes tipo 2 que tienen enfermedad cardiovascular aterosclertica o alto riesgo cardiovascular, independientemente del uso de metformina

Importantly, a 2023 meta-analysis of 38 randomized trials (3,600 patients) showed that postauricular injection led to significantly better hearing recovery than systemic steroids alone

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They slow gastric emptying so food sits in the stomach longer, creating a physical sensation of fullness

Diabetologia 66 (4), 657673