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Acrylic acid, an inhibitor of -oxidation pathway, inhibits the 3-ketoacyl-CoA thiolase activity [36, 37] when used at zero hours in the presence of 2-EH or 2-EHA (0.4 mg mL 1 ) in MSM, no growth of the test organism was detected, which confirmed the involvement of -oxidation pathway

Key lipids, including ceramides, sphingomyelins, phospholipids, diacylglycerols, and triglycerides, as well as branch-chain amino acids, have been found to be dysregulated in both ME/CFS and GWS (Germain et al., 2018, 2020

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