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Doses ranging from 1.5 to 3 grams per day for at least three months consistently show improvements in cognitive function several-fold greater than placebo, with significant improvements in attention, memory, and intellectual functioning

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Primaquine and Pamaquine are antimalarial drugs known to induce hemolysis in G6PD-deficient patients

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These findings suggest that metformin may slow the progression of OA and partially preserving cartilage integrity in the MIA-induced OA mouse model