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Rights and permissions About this article Cite this article Bensky, M.J., Ayalon-Dangur, I., Ayalon-Dangur, R

Intestinal innate immunity is generated by neutrophils, monocytes, macrophages, and DCs, as well as ILCs and NK cells, characterized by their capacity to produce a rapid and non-specific reaction as a first-line response [214]

Russian preclinical literature is the main evidence base

That distinction matters for clinicians designing care plans and for patients navigating an insurance landscape that still treats obesity and diabetes very differently

The scope of the review is intentionally selective rather than exhaustive, focusing on peptidereceptor systems that demonstrate biological plausibility, mechanistic coherence, and unmet therapeutic potential, yet lack approved therapeutic analogs or advanced clinical programs

By taking an informed approach to supplementation, we can all work towards a healthier, more vibrant life