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Patients perception of injectable therapy include perceived difficultly to use and fear of injections

In cases of failed convergence with log-binomial regression (for total AE and other AE), a modified Poisson regression was used to calculate RRs with 95% CIs from robust standard errors estimated using the sandwich estimator 41

Adverse outcomes include severe developmental abnormalities and embryo-fetal death

Originally developed to treat type 2 diabetes, semaglutide is a drug that has also shown surprising promise in the area of weight loss

Interestingly, the combination of semaglutide and trevogrumab alone (without garetosmab) was better tolerated, with discontinuation rates similar to semaglutide monotherapy, suggesting that garetosmab may contribute to the increased side effects in the triplet regimen

And if you are taking your semaglutide injection, consider timing it earlier in the day if evening dosing seems to affect your sleep