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Therefore, p53 is an important therapeutic target for keloids because of its crucial role in regulating apoptosis 7,8

Patients with high Kla scores show poorer responses to immune checkpoint blockade (ICB) therapy with higher disease progression rates, as ICB efficacy correlates closely with TME immune cell infiltration

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Across 26 months of consistent use, multiple studies have reported hair density gains of 3040% and shedding reductions of 2530% [5]

Furthermore, nanoencapsulation enables controlled and sustained release of active compounds, ensuring prolonged antimicrobial or antioxidant activity and thereby reducing the rate of food spoilage (190)