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In this review article, we aimed to update the understanding of the possible roles of HDACs in the pathophysiology of epilepsy, discuss the likely regulatory mechanisms of these enzymes and summarize the recent progress in the development of HDACi in epilepsy rodent models and patients

Staiger D, Stock JH

Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress

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Conclusions : It appears that 500 M and pathophysiological concentrations (800 M) of UA induce antioxidant cell response in J744A.1 macrophages proved by the indicative elevation GCL, GPx1, GR, and GS transcription