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In general, using these compounds is expected to be a new pathway to developing drugs for IS by suppressing ferroptosis

Topical application combined with H 2 O 2 effectively suppresses caries initiation and progression without adverse effects on oral mucosal tissues in vivo ( Ferumoxytol is a Food and Drug Administration (FDA)-approved nanoparticle formulation used for magnetic resonance imaging and the treatment of iron deficiency ( 2 O 2

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