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In ovaries, it modifies follicular support, endometrial repair, and local cytokine balance

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Targeted metabolomic analysis of head and neck cancer cells using high performance ion chromatography coupled with a Q exactive HF mass spectrometer

found that targeting cGAS and inhibiting lactylation modifications can promote the transition of microglia from the M1 phenotype to a repair phenotype [110], the addition of lactate has no effect on the expression of A2 astrocytes and only weakens M1 polarization process [57]

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