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We used to say that, oh my god, if you lift more than 20 pounds, you're going to explode and die, right

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Short answer: twice-daily = HUGE commercial disadvantage. Pfizer is reportedly working on a once-daily modified release version of danuglipron

Effect of metformin monotherapy on cardiovascular diseases and mortality: A retrospective cohort study on Chinese type 2 diabetes mellitus patients

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