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ML226 treatment resulted in HIF-1 stabilization, upregulation of HIF-1 target genes ( CAIX and VEGF ), and activation of a HIF-1 fluorescent reporter (HRE-GFP ODD ) in HeLa cells, similar to treatment with cell-permeable (DM-2OG

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A limited number of clinical studies were conducted to examine the effectiveness of melatonin in other neurodegenerative conditions, including ALS and MS

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