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It develops when there is excess fat in liver cells due to too much fatty acid uptake in the liver, excess synthesis of fat in the liver, and not enough fat exported out of the liver

Importantly we still do not know the impact they will have on patients who take them long-term

Lisofylline, a fat metabolism inhibitor which prevents buildup of ceramide a by product of fat metabolism in mouse skeletal muscle decreased the insulin resistance and thus appears to be a novel new approach for type 2 diabetes [141]

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