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However, while the final outcome of mitochondrial dysfunction is cell death, the phenotype of death (apoptosis and/or necrosis) depends on the level of cellular ATP, as ATP is required for the efficient assembly of the apoptosome

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In addition, the surface modification of BSA/AuNCs reduces unwanted intramolecular vibration and rotation 80 , enhances biocompatibility and stability, as well as diversifies the potential of BSA/AuNCs in biological applications 79

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In our study, we did not observe an increase in loose stools in NAC-treated animals during daily monitoring, consistent with previous research showing no toxicity after 30 days of high-dose NAC (1200 mg/kg/day) in rats [109]