It acts as a glucagon-like peptide-1 (GLP-1) analogue, enhancing insulin secretion and reducing glucagon secretion in a glucose-dependent manner
This is especially important for women and anyone over 40, populations where muscle preservation during weight loss is critical for long-term metabolic health
According to Brian Staiger, Pharm.D., of HelloPharmacist, Ozempic should be stored in the fridge before its first use, at a temperature between 36F and 46F
Semaglutide can also affect menstrual patterns , causing irregular or heavier periods in some women, likely related to hormonal changes that accompany significant weight loss
When used alone, the risk is low
However, the extreme calorie restriction can be difficult to maintain and may not be appropriate for everyone