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Over time, skin stretches to accommodate higher weight, and with sudden fat loss, collagen and elastin fibers can struggle to provide the same snapback. Skin elasticity declines with rapid loss: Collagen and elastin break down faster than they can rebuild when fat disappears quickly, leaving skin looking looser or crepey
Additionally, other hormones, like DHEA and pregnenolone, drop naturally with age, and consequently, during menopause as well
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640 In addition, under physiological conditions, zinc binds preferentially to MT, further activating MT to exert its anti-oxidative stress function
Clark R: The somatogenic hormones and insulin-like growth factor-1: stimulators of lymphopoiesis and immune function
