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19 Treatment Treatment of clinical vitamin B 12 deficiency has traditionally been accomplished by intramuscular injection of crystalline vitamin B 12 at a dosage of 1 mg weekly for eight weeks, followed by 1 mg monthly for life

Beyond collagen, GHK-Cu influences over 4,000 human genes, affecting approximately 31% of the entire genome

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In summary, for the reasons discussed we are maintaining our estimate for the hours associated with recordkeeping at 5 and our estimate of hours associated with reporting at 15, which equals 20 hours of annual burden per hospital and 60,760 hours of estimated annual burden across all 3,038 hospitals