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[6] [7] This brief duration has led to the development of GLP-1 receptor agonists (such as semaglutide and liraglutide), which are DPP-4-resistant analogues with prolonged half-lives, and DPP-4 inhibitors as therapeutic agents for type 2 diabetes

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It has recently been shown that ZIP13 is a crucial regulator of beige adipocyte biogenesis and thermogenesis

Nonetheless, the overlap between GLP-1 side effects and IBS symptoms means we need to look carefully at how these medications might exacerbate or alleviate IBS in different scenarios

doi: 10.1002/jms.3706

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