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Additionally, a recent research study investigates how 4-Octyl itaconate (OI), a form of itaconate functioning as a KEAP1 inhibitor, affects DSS-induced UC in mice (264)

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If retatrutide reduces major cardiovascular events (like semaglutide did in SELECT), the heart rate increase will be viewed as a pharmacologically interesting but clinically irrelevant side effect

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95 % CI (039, 010)