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Dosing protocols Phase 2 clinical trials used a titration schedule starting at 0.5mg weekly, escalating through 1mg, 2mg, 4mg, 8mg, and reaching maintenance doses of up to 12mg weekly over several months

Studies in vitro have shown that it can reduce levels of pro-inflammatory cytokines such as TNF- and the p-NFB marker, highlighting an overall anti-inflammatory effect

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3 Results 3.1 Participant characteristics The demographic characteristics of the participants are summarized in Table 1

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