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Mechanisms The MedDiet exerts its antihypertensive effects through synergistic pathways: endothelial function enhancement via eNOS activation and nitric oxide bioavailability, oxidative stress reduction through nuclear factor erythroid 2related factor 2-antioxidant response element pathway upregulation and nicotinamide adenine dinucleotide phosphate oxidase 4 inhibition

Ascorbic acid is a free radical, an antioxidant scavenger, and plays a major role in oxidation-reduction reactions

MOTS-C promotes fat oxidation through AMPK-mediated lipolysis and targets visceral fat specifically

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Altered spontaneous secretion and metabolic clearance of growth hormone in overweight youth