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The Bioethics Committee of the Poznan University of Medical Sciences approved the study protocol [149/24]

Bloody stool is rare, occurring in less than 1% of semaglutide users

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The half-life of paraxanthine is approximately 3.1 h, which is shorter than that of caffeine (4.1 h) but significantly different from theophylline (6.2 h) and theobromine (7.2 h) (Nehlig et al., 2018