A clinical trial involving 42 PD patients (2:1 randomized to NAC or control) demonstrated that a 3-month NAC regimen (50 mg/kg intravenous weekly plus 600 mg oral twice daily, skipping oral doses on infusion days) significantly increased dopamine transporter binding compared with the control group
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Diaconu et al., Failure of phospholipid hydroperoxide glutathione peroxidase expression in oligoasthenozoospermia and mutations in the PHGPx gene, Andrologia, 2006, doi: 10.1111/j.1439-0272.2006.00729.x
Therefore, synthetic GLP-1 RAs resistant to DPP-4 degradation have been developed
Glitazone has been shown to offer protection in animal models of Parkinsons ( Click here and here for more on this)
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