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The principal outcome - resolution of MASH in absence of fibrosis worsening - occurred in 40%, 36%, and 59% of individuals treated with semaglutide 0.1, 0.2, and 0.4 mg, respectively, vs

Moreover, it is well-established that intestinal barrier function is a crucial factor in the protection against allergies and infections, by preventing allergen and bacterial translocation from the gut lumen into the immune cell-populated lamina propria and mesenteric lymph nodes (105107)

mean reduction 4.4 vs 2.3 L/week

This can include minor headaches or temporary changes in digestion